A microarray is a multiplex lab-on-a-chip. It is a 2D array on a solid substrate (usually a glass slide or silicon thin-film cell) that assays large amounts of biological material using high-throughput screening methods
A microarray is a sample of a substance, like DNA, that is adheared to a solid surface. Usually these are glass slides used to view samples under a microscope.
A cDNA microarray is a hybrid of a DNA microarray, which is a collection of a number of minute DNA dots. These are mostly used in the field of genetic testing.
mRNA is extracted from cells for DNA microarray. the mRNA is then converted in the lab to cDNA this cDNA is allowed to interact with the probes on the microarray chip
it works by chips
Otherwise known as "microarray chips," DNA microarray are used to determined the genetic makeup of a given tissue sample. By shining various bands of light on these chips, the gene(s) in the tissue are expressed in the form of a particular color.
DO STEKEL has written: 'MICROARRAY BIOINFORMATICS'
Microarray analysis involves breaking open a cell, isolating its genetic contents, identifying all the genes that are turned on in that particular cell and generating a list of those genes.
DNA microarray analysis is a technique used to match up two strands of DNA. It is used in paternity tests and in criminal investigations in which a perpetrator's DNA was found at the crime scene.
Microarray data is usually applied for the comparison of gene expression profiles under different conditions. But we have to make sure what we are comparing is really comparable. So, to bring the data under common frame normalization is done. In technical terms, normalization of microarray data removes both random and systematic biases. [Source: Guide To Analysis of DNA Microarray Data]
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DNA Microarray
Step 1: Isolate the mRNA. Step 2: Make cDNA by reverse transcription using fluorescent labeled nucleotides. Step 3: Apply the cDNA mixture to a microarray with a different gene in each spot. Step 4: Rinse off excess DNA; scan for fluorescence.
The time of replication initiation can be measured through MICROARRAY ANALYSIS because it uses flourecent labelled nucleotide.