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What is microbial chronometer?

Updated: 10/23/2022
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11y ago

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Microbial chronometers (also called molecular chronometers) are, "nucleic acid and protein sequences that gradually change over time in a random fashion and at a steady rate, and which therefore can be used to determine phylogenetic relationships." Molecules that are sometimes used as chronometers include ATPases, however you cannot compare the ATPases that are used in respiration and fermentation due to their divergence, only same function molecules may be compared. AAtRNA synthetases, these may become the new standard way to define the phylogenic relationship of organisms due to their highly conserved nature. RecProteins, used in recombination however they are not very well conserved and so using them is not recommended (the most effective chronometer is highly conserved). Currently the small subunit of the ribosome is used (16s in prokayotes and 18s in eukaryotes) due to its conserved nature and presence in all organisms.

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