464 miles. I-70 West to I-57 South to I-55 South
Ohio
Take I-70 WEST from Indianapolis to I-57 SOUTH to MEMPHIS in Effingham, ILLINOIS.Take I-57 SOUTH to I-55 SOUTH to MEMPHIS at EXIT 1A in MISSOURI.Take I-55 SOUTH to I-12 WEST to BATON ROUGE at EXIT 29B in LOUISIANA.Take I-12 WEST to I-10 WEST in Baton Rouge.Take I-10 WEST to Houston.
The shortest distance is via route US-72 E. The shortest time is via route I-40 E and I-24 E.
In the shortest route the two largest would be Memphis and Nashville.
Through Houston, Texarkana, Memphis, Nashville and Louisville.
Shortest route 9 hours 7 mins. Longest route 10 hours 8 mins.
Take I-65 SOUTH to Nashville bypassing Indianapolis via I-465 SOUTH.
It is 821 miles of road driving distance via the shortest route according to Google Mapws.
The shortest route is on I-90 W.
Depending on the route, the drive should take between 9 hours to 9 hours and 30 minutes.
the shortest air route is a great circle
The shortest route is I-75 N.