what is the tblet hardness,what is its unit ,we aply hydraulic pressure on tablet compression mchine but in result we gain hardness on tablet,how the pressure is converted into hardness unit. Friability refers to the ability of the compressed tablet to avoid fracture and breaking apart during transport.
behnchood
bcoz of coating. And for transport
Tablet whiskering refers to the formation of fine, hair-like lines on the surface of a tablet. It is typically a cosmetic issue caused by the drying process during tablet manufacturing and does not affect the efficacy or safety of the medication.
Tablet hardness testing became available in the 1930's. Tablet hardness testing, is a technique used by the pharmaceutical industry to test the breaking point for the use, transportation, and storage of supplies.
Green lantern sinestro
tablet hardness units Kp and N has co-relation as below. Kp (kiloponds) = 10 N (Newton)
The Ability to crumble of sand is known as friability
friability F=I-F.100/I where I =Iinitial weight of tablets , F = weight after friability. Normal limit less than 1%.
In the tablet compression machine main principle is compressing the upper & lower puch in a die hole . the hydraulic pressure plays a key role if we increase the hydra. pressue more compressing force on tablet then it becomes more hard.
It depends on how friable the final wheel is to be. Binders can be synthetic or natural resins, mineral cements or glasses, in order of increasing hardness, decreasing friability.
keep the hardness of the tablets b/w 4-6 kg/(cm)2 using pfizer or monsento apparatus
Diamonds are the hardest substance on Moe's Hardness Scale and as such don't have a determined streak color (since streak is determined usually by a clay tablet of hardness ~3)