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What are the criteria for a substance in a neurotransmitter at a synapse?
Criteria required identifying a substance as a neurotransmitter 1- ) Synthesis of the substance: • It is synthesized in the neuron • Some substances are synthesized from the Tryptophan • Rate limiting step in its synthesis • Enzymes required in the synthesis of that substance are themselves synthesized in the cell body of neuron ,then distributed throughout the neuron • Mainly found in the cell body and nerve terminal • These enzymes are stored in the presynaptic terminal of neuron, inside the synaptic vesicles. 2- ) Storage of that substance: • The neutransmitter is stored inside the synaptic vesicle of nerve terminal 3- ) Release of the neurotransmitter: • It is released from the nerve terminal usually through Ca++ dependent process following the stimulation of the nerve fiber by action potential. • Fusion of the synaptic vesicle with the nerve membrane releasing neurotransmitter outside the nerve fiber into the synaptic cleft. 4- ) Exogenous analogue (drug) of the neurotransmitter: • If drug analogue of the neurotransmitter is injected exogenously, it should mimic the same mechanism of action as done by the endogenously released neurotransmitter.
What mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell increasing or decreasing the activity of that cell?
agonists Chemical substances that mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. Drug that enhances the effects of a particular neurotransmitter.
Is calcium a neurotransmitter?
No, calcium itself is not a neurotransmitter BUT it is highly important in the process of the action potential. The action potential triggers the influx of calcium at the end of the terminal bouton, causing the influx of Ca2+ into the cell and this triggers for the release of the neurotransmitter. :)
What substance crosses the gap between a neuron and a muscle fiber?
This substance is called as neurotransmitter. Here it is acetylcholine.
A neuron will generate action potentials when it?
A neuron will generate action potential when it is stimulated by a neurotransmitter.
What is a chemical substance that mimics the action of a neurotransmitter?
Agonists
What neurotransmitter does caffeine mimic?
adenosine
Amphetamines mimic the effects of the neurotransmitter?
epinephrine
Anagonist defininition in human anatomy?
A mimic of a neurotransmitter. Not the exact neurotransmitter, but works in the same way.
What are the criteria for a substance in a neurotransmitter at a synapse?
Criteria required identifying a substance as a neurotransmitter 1- ) Synthesis of the substance: • It is synthesized in the neuron • Some substances are synthesized from the Tryptophan • Rate limiting step in its synthesis • Enzymes required in the synthesis of that substance are themselves synthesized in the cell body of neuron ,then distributed throughout the neuron • Mainly found in the cell body and nerve terminal • These enzymes are stored in the presynaptic terminal of neuron, inside the synaptic vesicles. 2- ) Storage of that substance: • The neutransmitter is stored inside the synaptic vesicle of nerve terminal 3- ) Release of the neurotransmitter: • It is released from the nerve terminal usually through Ca++ dependent process following the stimulation of the nerve fiber by action potential. • Fusion of the synaptic vesicle with the nerve membrane releasing neurotransmitter outside the nerve fiber into the synaptic cleft. 4- ) Exogenous analogue (drug) of the neurotransmitter: • If drug analogue of the neurotransmitter is injected exogenously, it should mimic the same mechanism of action as done by the endogenously released neurotransmitter.
What is the substance released at axon terminals?
The substance that is released at an axonal ending to propagate the nerve impulse to the next nerve or muscle is called
What mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell increasing or decreasing the activity of that cell?
agonists Chemical substances that mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. Drug that enhances the effects of a particular neurotransmitter.
True or False A neurotransmitter substance crosses the synaptic cleft between a nerve and muscle fiber and stimulates the nerve to have an action potential?
False
Is calcium a neurotransmitter?
No, calcium itself is not a neurotransmitter BUT it is highly important in the process of the action potential. The action potential triggers the influx of calcium at the end of the terminal bouton, causing the influx of Ca2+ into the cell and this triggers for the release of the neurotransmitter. :)
What is imitate mean?
Mimic means to copy in action or speech. For example, parrots can mimic
Mimic?
to imatate or copy an action
What substance crosses the gap between a neuron and a muscle fiber?
This substance is called as neurotransmitter. Here it is acetylcholine.
