among many drugs causing hemolytic anemia one is Alpha methyl dopa a centrally acting antihypertensive used most in pregnant womens to control blood pressure.
There are quite a few causes for Hemolytic Anemia, they include: . Deformity of the red blood cells - so they break down quicker. . Drugs taken for another illness . Caused from another blood disease. . Or harmful substances.
Hydrochlorithyzide 1956
Specific drug references should be consulted, since interactions vary for antihypertensive drugs.
verapamil
it is antihypertensive drug(renin- angiotensine coverting enzyme inhibitors)
Antihypertensive
DefinitionDrug-induced immune hemolytic anemia is a blood disorder that occurs when a medicine triggers the body's defense (immune) system to attack its own red blood cells. This causes red blood cells to break down earlier than normal.See also: Hemolytic anemiaAlternative NamesImmune hemolytic anemia secondary to drugs; Anemia - immune hemolytic - secondary to drugsCauses, incidence, and risk factorsIn some cases, a drug can cause the immune system to mistakenly think your own red blood cells are dangerous, foreign substances. Antibodies then develop against the red blood cells. The antibodies attach to red blood cells and cause them to break down too early.Drugs that can cause this type of hemolytic anemia include:Cephalosporins (a class of antibiotics)LevodopaMethyldopaPenicillin and its derivativesQuinidineSome nonsteroidal anti-inflammatory drugs (NSAIDs)There are many other rarer causes of drug-induced hemolytic anemia. This includes hemolytic anemia associated with glucose-6 phosphate dehydrogenase (G6PD) deficiency. But in this case, the breakdown of red blood cells is due to a certain type of stress in the cell, not the body's immune system.Drug-induced hemolytic anemia is rare in children.SymptomsDark urineFatiguePale skin colorRapid heart rateShortness of breathYellow skin color (jaundice)Signs and testsA physical examination may show an enlarged spleen. A number of blood and urine tests may be done to help diagnose this condition.Tests may include:Absolute reticulocyte countDirect or indirect Coombs' testIndirect bilirubin levelsRed blood cell countSerum haptoglobinUrine chemistryTreatmentStopping the drug that is causing the problem may relieve or control the symptoms.Some persons may be given a medicine called prednisone to reduce the immune response against the red blood cells. Special blood transfusions may be needed to treat severe symptoms.Expectations (prognosis)Most patients have a good outcome if they stop taking the drug that is causing the problem.ComplicationsDeath caused by severe anemia is rare.Calling your health care providerSee your health care provider if you have symptoms of this condition.PreventionYou should continue to avoid the drug that caused this condition.ReferencesSchwartz R. Autoimmune and intravascular hemolytic anemia. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 164.
ACE inhibitors
Macrocytic anemia is a condition where the red blood cells are larger than they should be. They are usually larger and there usually is a lower number than there should be.
Recommended dosage varies with patient, drug, severity of hypertension, and whether the drug is being used alone or in combination with other drugs.
Facts and Comparisons
This drug contains illegal drug witch is found in a dangerous sickness talk to a doctor when taking this you could be in a death situation!