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  1. Take I-40 EAST to I-85 NORTH to DURHAM in North Carolina. In Tennessee, you will bypass two cities: you will bypass Nashville by taking I-440 EAST (EXIT 206 off I-40) and you will also bypass Knoxville by taking I-640 EAST (EXIT 385 off I-40).
  2. Take I-85 NORTH to Durham.
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Q: What is the best route to take to get to Memphis TN from durham NC?
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