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Take a flight. There are several airlines flying from Mexico City to Puerto Vallarta every day, and flight times rarely surpass one and a half hours.

The other option is taking a bus or driving, but trip times are around 9 to 10 hours, so if you can afford it, best take a flight at Mexico City's international airport.

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11y ago
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Q: What is the best way to go from Mexico city to puerto vallarta?
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