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From Webster's Dictionary:
thalidomide
; Main Entry: : tha·lid·o·mide ; Pronunciation: : \thə-ˈli-də-ˌmīd, -məd\ ; Function: : noun ; Etymology: : phthalic acid + -id- (from imide) + -o-+ imide ; Date: : 1958 : a drug C13H10N2O4 that was formerly used as a sedative and is now used as an immunomodulatory agent especially in the treatment of leprosy and that is known to cause malformations of infants born to mothers using it during pregnancy
Credit: Merriam-Webster's Online Dictionary
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What causes the thalidomide production of a baby with no arms or legs?
Thalidomide was prescribed for morning sickness in pregnancy before the devastating effects were known. Thalidomide affects angiogenesis which is the process in which new blood vessels form. By preventing the formation of these new vessels to take place, directly resulting in babies being born with no limbs.
What does dermalogically tested mean?
It means it has been tested on human skin.
What organs are not tested in an autopsy?
lungs
What does a sperm donor get tested for before they are able to donate?
Well they obviously would be tested for any STDs and maybe if they have a history of birth defects.
What antibodies are tested for by Selectogen I and II?
IgG
Why did thalidomide go wrong?
Thalidomide all went wrong because it wasn't tested properly and they skipped some vital tests before it was used on actual patients.
What did researchers not do when testing thalidomide?
They tested the drug on animals, which was not a very good thing to do research wise either way, but on top of that, they didn't test it on pregnant animals.
Who invented thalidomide?
Dr.R.Kunz and Dr.H.Keller invented thalidomide in Germany
How has thalidomide affected the way in which drugs are tested and marketed today?
It increased the awareness of the need to look at safety profiles closer, especially in pregnant women and children (or fetuses).
How did thalidomide has affected the way in which drugs are tested and marketed today?
It increased the awareness of the need to look at safety profiles closer, especially in pregnant women and children (or fetuses).
How did Thalidomide help pregnant women?
Thalidomide was supposed to be an effective sedative for pregnant women, but thalidomide caused birth defects and peripheral neuropathy.
What are some books about the thalidomide disaster?
Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine by Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicineby Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom
How does the drug thalidomide work?
Thalidomide regulates the immune response by suppressing a protein, tumor necrosis factor alpha.
How did thalidomide affect babies?
Thalidomide leads to the forming of deformed and flipper like limbs in babies.
What are some drugs that were successfully tested on animals but affected humans badly?
I only know of one so far, and it is Thalidomide. It caused serious birth defects in the babies of the pregnant women who took this drug.
What is the chemical formula of thalidomide?
C13H10N2O4
What actors and actresses appeared in Happy Birthday Thalidomide - 2004?
The cast of Happy Birthday Thalidomide - 2004 includes: Mat Fraser
