They both are enzymes related to ATP. The difference lies in that ATPase breaks down ATP while ATP synthase synthesizes ATP.
ATP is spent transporting pyruvate and ADP into the mitochondrial matrix. Protons leak across the inner mitochondrial membrane without using ATP synthase.
ATP synthase
When ATP loses inorganic phosphate, Pi, through ATPase, you get ADP
When a new hydrogen ion enters, the top part of the ATP synthase complex rotates.The hydrogen ions provide energy for the synthesis of ATP molecules.ÊÊ
three H+ protons
It's either ATP synthase (if you are studying the end of the ETC part of respiration, where ADP is converted to ATP) through substrate-level phosphorylation or nucleoside-diphosphate kinase (if you are looking at the transfer of a P* from, say, GTP to ADP to make ATP and GDP) through oxidative phosphorylation.
The enzyme is ATP synthase (sometimes referred to as "ATP synthetase").It catalyzes the synthesis of ATP from ADP and free inorganic phosphate. It is a remarkable enzyme, part of which spins round. In fact, ATP synthase has been called a molecular machine.To see an image, use the link below.
Most ATP is synthesized from ADP and inorganic phosphate by ATP synthase (FoF1, or F-type ATPase). This enzyme is present in mitochondria, in chloroplasts and in bacteria.
ATP synthase catalyzes the addition of a phosphate group to an ADP molecule. ADP + ATP synthase + P --> ATP + ATP synthase (ATP synthase on both sides of the equation indicates that, as an enzyme, it is not used up in the reaction.)
The rotor part of the ATP synthase enzyme.
The electron transport chain (ETC) is conducted in the mitochondria. The four complexes of the ETC, along with the enzyme that produces ATP (known as Complex V, ATP synthase, or F0F1-ATPase), are located in the inner mitochondrial membrane.
ATP synthase allows H+ ions to pass through the thylakoid membrane.
ATP is spent transporting pyruvate and ADP into the mitochondrial matrix. Protons leak across the inner mitochondrial membrane without using ATP synthase.
The catalytic knobs of ATP synthase would be located on the stromal side of the membrane. Protons travel through ATP synthase from the thylakoid space to the stroma.
ATP synthase is involved in making ATP + P at the membrane in the mitochondria. This occurs at the beginning of the Krebs cycle.
They are found in mitochondria and in chloroplasts.In mitochondria, the ATP synthase complexes are embedded in the inner membrane. In chloroplasts, the ATP synthase complexes are embedded in the thylakoid membranes.
ATP synthase