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Benadryl (at least, the box I have) contains three different medicines - one of which is phenylephrine, which is often used instead of pseudoephedrine (pseudoephedrine has gained a bad rep as a precurser to methamphetamine). There is some question about the effectiveness of phenylephrine, though studies have shown it performs much better than a placebo, even if it's not as effective as pseudoephedrine.

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Q: What is the difference between Benadryl and pseudoephedrine?
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