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An antigen can be anything from virus to bacteria to a soluble protein from outside or inside a cell. This includes both foreign and self peptides. An antibody that finds an appropriate antigen will bind to it and your B and T cells determine if it's self or not.

A processed antigen came from cytosol. A protein will be taken by ubiquitin to a proteosome where it is broken up into small peptides. These peptides will make their way into the endoplasmic reticulum (through TAP) where they are exposed to MHC's.

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Q: What is the difference between a antigen and a processed antigen?
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