Any foreign particle interact with Antibody or T cell is antigen. Interaction is non-covalent and highly specific.
Antigen that evoke immune response is called Immunogen. An immunogen usually has a fairly high molecular weight (usually greater than 10,000), thus, a variety of macromolecules such as proteins,lipoproteins, polysaccharides, some nucleic acids, and certain of the teichoic acids, can act as immunogens.
An Antigen is considered as any foreign particle that enters the body such as dust, food and any microorganisms. An Immunogen is any foreign particle that triggers an response from the body's immune system. Consequently, all Immunogens are Antigens, but not all Antigens are Immunogens. To be considered an Immunogen, the particle has to have all the following characteristics: 1- Has enough atomic mass to be recognized by T cells and Antigen Presenting cells 2- Be significantly different from all of our cells or metabolites. 3- Must have a defined secondary and tertiary structure (has to be firm to form an epitope) 4- Has to be an antigen eg: Carbohydrates are not a highly immunogenic antigen, since they are made of glucose which is essential for our body's metabolism. Moreover, our body has the ability to store glucose as glycogen. An Adjuvant is a compound that increases the immunogenicy of antigens when mixed together.
widal slide is easier and it save time but widal tube test is not easy and it takes time.
An antigen can be anything from virus to bacteria to a soluble protein from outside or inside a cell. This includes both foreign and self peptides. An antibody that finds an appropriate antigen will bind to it and your B and T cells determine if it's self or not. A processed antigen came from cytosol. A protein will be taken by ubiquitin to a proteosome where it is broken up into small peptides. These peptides will make their way into the endoplasmic reticulum (through TAP) where they are exposed to MHC's.
MHC (major histocompatability complex) is the term for the molecules in all vertebrates. HLA (human leukocyte antigen) is the specific term for that class of molecules in humans.
A antigen
An Immunogen is foreign particle that triggers the body's immune system where as Antigen is also a foreign particle , due to its low molecular weight it is unable to trigger immune system. Example for antigen is Hapten
Some antigen types include bacterium and immunogen.
An antibody is a glycoprotein that is produced by plasma cells. It consists of heavy chains and light chains. An antigen is a molecule that interacts with an antibody (or T-Cell). When the antigen interaction induces an immune response it is known as an immunogen.
An Antigen is considered as any foreign particle that enters the body such as dust, food and any microorganisms. An Immunogen is any foreign particle that triggers an response from the body's immune system. Consequently, all Immunogens are Antigens, but not all Antigens are Immunogens. To be considered an Immunogen, the particle has to have all the following characteristics: 1- Has enough atomic mass to be recognized by T cells and Antigen Presenting cells 2- Be significantly different from all of our cells or metabolites. 3- Must have a defined secondary and tertiary structure (has to be firm to form an epitope) 4- Has to be an antigen eg: Carbohydrates are not a highly immunogenic antigen, since they are made of glucose which is essential for our body's metabolism. Moreover, our body has the ability to store glucose as glycogen. An Adjuvant is a compound that increases the immunogenicy of antigens when mixed together.
A soluble antigen is a viral antigen that remains after the virus has been removed. A particulate antigen is produced by particles such as dust and germs.
Antigen binding site or epitope is a part of an antigen that is recognized by the antibody. Paratope is a part of an antibody that binds on epitope.
the most effective immunogen is proteins
When mixed with an immunogen, it enhances the immune response against the immunogen
mention factors affecting antigenicity 1) molecular weight of antigen. e.g. protein is a good antigen as compare to lipid or nucleic acid. 2) invecivness of antigen, that is due to toxins or chemicals secreted by the antigen 3) degredibility: antigen should be degreted in body so that body immune system can react against them. 4) complexicity of antigen
an aepitope is the part of an antigen where antibodiy or lymphocyte receptor binds
widal slide is easier and it save time but widal tube test is not easy and it takes time.
difference between an antibody and an antigen