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Closed means just that...not open and unable to allow sodium ions to flow. Inactivated means that they do not respond to the stimulus. They could be open or closed, but do not receive the signal from the messenger. Also refractory.

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7y ago
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1w ago

Inactivated sodium channels are unable to open and conduct ions due to the presence of a blocking particle, whereas closed sodium channels are capable of opening and conducting ions when stimulated. Closed channels are in a resting state and can be activated by a depolarizing signal, while inactivated channels are temporarily unable to conduct ions after being activated.

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Q: What is the difference between inactivated sodium channels and closed sodium channels?
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