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What is the dissolution method for atorvastatin tablets if you want to analyze by uv spectroscopy?

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November 27, 2008 7:02AM

the best conditions for atorvastatin calcium 10 mg tablets is as the following dissolution media is 0.05 potassium dihydrogen phosphate buffer PH is 6.8 use paddle II 75 rpm for 45 min make standard dilution in the same media and max abs. is almost at 243 nm for higher conc of atorvastatin use sodium lauryl sulphate 0.5 %