217 miles taking this route:
about 150 miles
187 miles on NY-17
About 3.5 - 4 hours
It is 278.39 miles according to MapQuest.
If that's Rhinebeck, the distance is 60 miles.
It is 56.3 miles according to Google Maps.
The address of the Museum Of Rhinebeck History is: 7015 Route 9, Rhinebeck, NY 12572
From Manhattan (which I just chose for a standard NYC location) to Rhinebeck, NY is about 115 miles. Driving it takes about 2 hours, 15 minutes or you can take either Amtrack (from Penn station) or the MTA train (from Grand Central Terminal) to Kingston, NY. From Kingston, Rhinebeck is only 12 miles.
Baldwinsville is in Onondaga County NY. It is close to Syracuse, NY which is quite near the East-West middle of the state ... south of Lake Ontario.(and they get a LOT of snow there!)
They are right across the Hudson River from each other. To cross the river, take the KINGSTON-RHINECLIFF BRIDGE on NY-199.
1752 miles
Fishkill, New York is halfway between Ossining & Rhinebeck