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enzymatic activity is pH specific. Alteration of pH of media causes ionization of amino acids. Acidic amino acids have additional carboxyl functional groups . Basic amino acids have additional amino functional groups As a result of ionization, 3-D structure existing on the base of IONIC BONDS is altered. Moreover shape is also effected. catalytic activiyty is effected.

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9y ago
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12y ago

trypsin is most active at ph 7-8.5. In acid phs Trypsin is denatured and at very alkaline phs trypsin is also denatured

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Q: How does pH affect protease activity?
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