protease will digest protein
Temperature, pH, organic solvent, mechanical forces
An enzyme is a folded protein. When this folded protein becomes denatured, it essentially stops working. It can not function due to high temperatures or wrong pH.
pH is a major determinant of protein structure. The function of a protein is directly related to its structure. For example, pepsin (a proteinase- a protein-digesting enzyme) is functional in the low pH of the stomach because the pH of the stomach provides a suitable environment for proper folding, interactions, and the overall shape of the protein. In the small intestine, where the pH is much higher, it has a significant decrease in activity because this is no longer a favorable environment for the protein.
Pepsin. It is located in the stomach. Pepsin helps with the breakdown of food and is a protein. A pH 2 is optimal for the human enzyme pepsin. If the pH level exceeds 7, pepsin becomes denatured or lose its structure; above pH 5,, it will increase function.
The optimum pH and optimum temperatures of an enzyme are simply levels that the enzyme work most effectively at. These levels contribute to factors such as the enzyme's protein structure. Different levels of pH and temperature can alter the integrity of the protein, this process is called denaturation. When an enzyme undergoes denaturation, its level of activity is inhibited by failure of the substrate to effectively attach itself to the active site.
The general term is "proteases" Pepsin cleaves at the "n" terminus produced by the stomach and works in an acidic pH environment. Chymotrypsin and Trypsin are produced by the pancreas which is below the stomach and work in a more basic pH environment.
The active site of an enzyme can very much be influenced and damaged by a very high pH level. An enzyme is a protein, and because of that it is very sensitive to pH levels. High pH can denature a protein, and thus "damage" the active site.
becuase it soor your face! aww u gnna take that !@£$%&*?
Temperature, pH, organic solvent, mechanical forces
An enzyme is a folded protein. When this folded protein becomes denatured, it essentially stops working. It can not function due to high temperatures or wrong pH.
The main enzyme in the Stomach is Pepsin which is used to digest protein. Only protein digestion occurs in the stomach and almostt no absorption, (only a little alcohol). This protein is not secreted as its active form (ie not as pepsin) but as the Zymogen (the inactive precursor to proteins) Pepsinogen which cleaves in a low pH to form the active enzyme.
Decrease in pH of the stomach will distort the active site of the enzyme pepsin, which affects its action.
Enzymes are designed to work at their optimum pH. This is the level at which they will work the fastest. If the pH around an enzyme becomes too high or too low, the protein structure of the enzyme will be denatured. This is a irreversible effect, and the enzyme cannot carry out its function, and is thus useless (you can think of it as dead)
pH is a major determinant of protein structure. The function of a protein is directly related to its structure. For example, pepsin (a proteinase- a protein-digesting enzyme) is functional in the low pH of the stomach because the pH of the stomach provides a suitable environment for proper folding, interactions, and the overall shape of the protein. In the small intestine, where the pH is much higher, it has a significant decrease in activity because this is no longer a favorable environment for the protein.
The enzyme has an optimal point of pH at which the enzyme works best. For example a catalase enzyme works best in a pH of 7. When the pH changes it denatures the enzyme causing it to not be able to react with the substrate.
enzymes are proteins. when you denature a enzyme you destroy the protein structure/shape. it happens a couple of ways; 1) temperature (they have a 'optimum temperature') at certain temperatures enzymes are denatured 2) Ph, again, they have a 'optimum pH at which they work best, and certain pH levels where they are denatured. 3) Various chemicals..
Pepsin. It is located in the stomach. Pepsin helps with the breakdown of food and is a protein. A pH 2 is optimal for the human enzyme pepsin. If the pH level exceeds 7, pepsin becomes denatured or lose its structure; above pH 5,, it will increase function.