The active site of an enzyme can very much be influenced and damaged by a very high pH level. An enzyme is a protein, and because of that it is very sensitive to pH levels. High pH can denature a protein, and thus "damage" the active site.
Denature - if it is to do with biology than it is the fact that at high temperatures, An Enzyme`s active site will change in shape, It is now Denatured.
At temperatures after the optimum for the enzyme , the enzymes become denatured. This is because the active site of the enzyme becomes distorted , meaning no substrates can bind with the site in anabolic/catabolic reactions. The polypeptides that make up these enzymes unravel , which changes the quaternary structure , causing this distortion of the active site. I hope this is what you're looking for , ORCA-93 :)
An enzyme becomes denatured when: A) the temperature exceeds the optimum temperature for that enzyme (ie the temperature that it works best at) B) the pH of the surrounding of the enzyme is too low or too high for the optimum pH for that enzyme. When enzymes are heated up too much they vibrate so vigorously that the bonds holding the protein structure in its specific shape becomes broken. The enzyme shape changes and the substrate no longer fits in to the active site. An enzyme which has become denatured is permanently inactive and will take no further part in reactions.
Levels of interaction refer to the varying degrees of engagement between users and a system, often categorized into three main types: low, medium, and high interaction. Low interaction typically involves minimal user input, such as passive consumption of content. Medium interaction allows for some user feedback and participation, such as commenting or sharing. High interaction encompasses active and dynamic engagement, where users can create, modify, or influence content extensively.
Elevated LD, or lactate dehydrogenase, in a blood test typically indicates tissue damage or cell death. LD is an enzyme found in many tissues throughout the body, and increased levels can be seen in conditions such as heart attack, liver disease, muscle injury, or certain cancers. Further investigation is usually needed to determine the specific cause of the elevated LD levels and to guide appropriate treatment.
In the active site, with high affinity.
liver is an organic compound that contains HIGH levels of catalase (enzyme)
alters the active site of the enzyme
The body has its own normal temp. And enzymes function along with body temp, you go to high or low it can cause severe damage to the body. Enzymes are proteins, and they are denatured (change in structure) when expose to high temps.
The active site of an enzyme is where the substrate binds and undergoes a chemical reaction. It is a region on the enzyme molecule where catalysis takes place. The active site has a specific shape that allows it to interact with the substrate with high specificity.
alters the active site of the enzyme
There are many conditions that render enzymes denatured. They are:- 1. Temperature (high heat sometimes cold) 2. pH( acid sometimes basic) 3. Oxidation Hope this helps.
Denaturation caused by high temperatures or extreme pH levels can change the shape of an enzyme, disrupting its active site and preventing it from binding to its substrate effectively. Additionally, the presence of inhibitors or competitive molecules can also alter the enzyme's shape, leading to a reduction or loss of enzyme activity.
That sounds a littel high. What are your liver enzyme levels? and are you jaundice?
High oxygen levels inhibit photosynthesis because oxygen competes with carbon dioxide for the active site on the enzyme RuBisCO, which is essential for the first step of photosynthesis. This competition reduces the efficiency of carbon dioxide fixation and ultimately hinders the overall process of photosynthesis.
This is known as denaturation. High temperatures can disrupt the bonds holding the enzyme's active site in its specific shape, leading to a permanent change in its structure that impairs its function. Once denatured, an enzyme may no longer be able to bind to its substrate effectively.
Shape. When an enzyme is overheated the bonds between molecules that make up the enzyme breaks, this changes the shape of the enzyme's active site. And as the enzyme is highly specific and would only work on one substrate which fits its active site, the enzyme will be totally denatured and won't activate anymore if it loses its shape.