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It depends on what term you mean. the brain is effected on a short term basis, but drinking too much can severly damage it. your kidneys and liver are also damaged but i would say your liver is most altereed and damaged by alchol

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15y ago
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13y ago

The - well the blood is an organ so the blood is first but the blood then takes it to the liver.

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12y ago

Basically, the stomach, although alcohol is absorbed in the mouth and esophagus and if inhaled first, it would be the lungs.

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12y ago

The major organ is the intestines, followed in importance by the stomach.

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12y ago

Stomach

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Q: What organ is first to absorb alcohol?
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