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Q: What is the formulation strategies for sustained release of materials into oral cavity?
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Which polymer are used in sustained release drug formulation?

A combination of various polymers are used such as Hydroxypropyl cellulose, carboxymethyl cellulose and many others. These sustained release (XR, ER, SR) tablets may or may not be film coated as well.


If a standard injectable form of a drug is given every 12 hours is the sustained release form more likely to be given every 6 hours or 96 hours?

More likely would be every 96 hours - the sustained release form is the formulation that keeps blood levels of the drug elevated for longer periods of time than the standard formulation.


What is matrix tablet?

Matrix tablet is a specific formulation intended for slow/controlled/sustained release of drug at a desired location in gastro-intestinal tract.


What are the factors influencing oral sustained- release dosage form design?

Factors influencing oral sustained-release dosage form design include drug properties (such as solubility, stability, and half-life), desired release profile, site of absorption in the gastrointestinal tract, manufacturing feasibility, patient compliance, and regulatory requirements. Additionally, considerations such as cost-effectiveness, formulation complexity, and technology advancement may also impact the design of sustained-release dosage forms.


What are the difference between Concerta and adderall xr?

Most simply, they are two different drugs. Concerta is a sustained-release formulation of methylphenidate, and Adderall XR is an extended-release formulation of a mixture of amphetamine salts. It's like the difference between Ritalin and Adderall, which are the immediate-release forms. Both drugs are stimulants, usually prescribed for ADD/ADHD. Methylphenidate is said to not be as strong a stimulant as amphetamine, but is still controlled as tightly.


Is inmecin-R a sustained release capsule?

Yes,Inmecin R is a sustained release capsule


How you can calculate the maintenance dose in the formulation of controlled release tablets?

Dt = Dose (1 + 0.693 × t/t1/2) Where, Dt = Total dose, Dose = Immediate release dose, t = Total time period for which sustained release is required, t1/2 = Half-life of drug.


What is difference between extended release and sustained release in the welbutrin?

sustained release dosage form follows first order kinetics.


What is the difference between Hcl or ER?

When those letters are used after a medication name, Hcl is likely to be the immediate release formulation, and ER the extended release formulation.


What is the difference between bio melatonin and melatonin?

Bio-Melatonin is a branded product containing 3mg of melatonin in an immediate release formulation.


What are the sustained release polymers?

HPMC, Ethyl cellulose, CAP..


What dosage form does Phenytoin come in?

Sustained-release capsules.