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Both macrophages and dendritic cells are formed from the same precursor cell, the monocytes. However, the two cells serve different functions during an infection. Macrophages remain in the area of the infection and phagocytosis (engulf) foreign invaders and dead cells. Dendritic cells leave the infected tissue and travel to local lymph tissue in order to alert the adaptive immune system.
deep in the cortex.
In the medullary cords = plasma cells & B Cells In the medullary sinus = macrophages B cells and T cells freely float around in all lymph nodes and lymph organs.
The Medulla is the inner region of a lymph node. It contains B cells, plasma cells, and macrophages.
The thymus contains large numbers of T cells and scattered dendritic cells, epithelial cells and macrophages. Immature T cells migrate from red bone marrow to the thymus, where they multiple and begin to mature. Lymph nodes filter lymph, which enters a node through one of several afferent lymphatic vessels. As lymph flows through the node, foreign substances are trapped by reticular fibers within the spaces between cells. Macrophages destroy some foreign substances by phagocytosis and lymphocytes destroy other by a variety of immune responses. Plasma cells and T cells that have divided many times within a lymph node can also leave the node and circulate to other parts of the body.
B Cells and macrophages
Macrophages
1. Neutrophil 2. Macrophage 3. Dendritic
Dendritic cells. They will take in pathogens and present them on MHC's (class 1 or class 2) depending on the nature of the pathogen. Dendritic cells will travel to your secondary lymph system (lymph nodes) for the pathogen to be identified and appropriately responded to.
lymph nodes are made out of lymphoid tissuethat is able to receive the lymph and return cleaned lymph back into the circulation. Generally the cell types found in the lymph nodes are antigen-presenting cells (specifically dendritic cells), T cells (both helper CD4 T cells and killer CD8 T cells) and B cells (which produce antibodies).
Langerhans cells are a subset of dendritic cells that reside in the epidermis (Part of the immune system). They have long dendrites (like arms) that capture antigen in the skin, and when they find an antigen, they migrate to lymph nodes and present to T cells allowing the adaptive immune system to respond.
some B lymphocytes are taken by macrophages to lymph nodes during the invasion the pathogen. The macrophages the exposes the pathogen's antigens to the B cells in the lymph nodes,The B cells with the matching receptor of the specific antigens respond by dividing repeatedly by mitosis, producing huge numbers over a few weeks.