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What is the normal function of the retinal blastoma gene?
tumor suppresser gene which codes for a protein that regulates E2F protein which is a cell cycle controller
How are the knockout mice useful in determining the function of genes?
Knock out mice are produced by impairing or deleting a particular gene expression. Thus the gene function (which was deleted) can be tracked by studying this knock out and the control mice. Lets say a gene is suspected to trigger immune response against a pathogen, one can study this by infecting the wild type(normal) and knock out(specific gene deleted) mice and study the role of the gene.
What is meant by gene knockout testing?
A knockout organism is an organism that's missing a functioning gene. They're used to test the function of genes and genetic diseases, because a researcher can observe specific changes in a gene knockout organism's gene expression and traits.
What function perform bobbed gene?
Bobtails are reduced tail in some Drosophila, its production is controlled by a gene which is called bobbed gene which is a recessive gene. So to produce the bob-tailed offsprings both the parents must be bobtailed. Munib-ur-Rahman
What is in vitro mutagenesis and what does it help the scientist understand?
In vitro mutagenesis is a technique to discover the function of a gene by introducing specific changes into the sequence of a cloned gene, reinserting the mutated gene into a cell, and studying the phenotype of the mutant.
Where is the multiple cloning site present in pUC 18?
It is within the LacZ' gene.
What is the birth name of Marian Lacz?
Marian Lacz's birth name is Marian Mikolaj Lacz.
How tall is Laura Lacz?
Laura Lacz is 168 cm.
How tall is Marian Lacz?
Marian Lacz is 182 cm.
What nicknames did Marian Lacz go by?
Marian Lacz went by Makus.
When was Laura Lacz born?
Laura Lacz was born on October 25, 1954, in Warsaw, Mazowieckie, Poland.
When was Marian Lacz born?
Marian Lacz was born on December 5, 1921, in Rzeszw, Podkarpackie, Poland.
When did Marian Lacz die?
Marian Lacz died on August 2, 1984, in Warsaw, Mazowieckie, Poland.
Explain the principle of insertional inactivation by giving a suitable example?
insertional inactivation is basically about the inactive of second marker where the protein cannot be longer produced. the suitable example is pUC19 where the lacZ gene that encoded for beta-galactosidase cannot be longer produced when the foreign gene is inserted in it..
What is the definition of microbial genetics?
it is the study of gene and gene function in micro organisms.
How is it possible for a point mutation to have no effect on the function of gene?
If the point mutation does not change the protein to be translated in the 3-letter sequence, then it will have no effect on the gene's function.
Who determines gene function?
genetic engineer
