This is the deepest layer of the skin structure and, as such, acts as stem cells since they are the least differentiated or least specific type of skin cell. As they migrate upward, environmental factors and neighboring cells increasingly cause them to become more specific cell types. Ocassionally called the "basement membrane," found to be essential for proper healing after thermal injuries to the skin. Was eventually found to be the reason why earlier attempts at skin grafts using only upper skin cells were found not to be effective in 3-rd degree full thickness burns. Modern skin grafts now use a layer of these stratum g. cells on the artificial skin, followed by other cells added later. The result has been a marked improvement in the rate of successful skin grafts.
Three type of cells occupy the stratum basale: Keratinocytes, Melanocytes and tactile cells.
The keratinocytes are the most abundant cell type in the epidermis and are found throughout all epidermal strata. The stratum basale is dominated by large keratinocyte stem cells,which divide to generate new cells that replace dead keratinocytes shed from the surface. Their name is derived from their synthesis of Keratin, a protein that strengthens the epidermis considerably.
The Melanocytes have long branching processes and are scattered among the keratinocytes of the stratum basale. They produce and store the pigment melanin in response to ultraviolet light exposure. Their cytoplasmic processes transfer pigment granules, called melanosomes, into the Keratinocytes within the basal layer and sometimes in more superficial layers. This pigment ( which includes the colors black,brown,tan,or yellow-brown) accumulates around the nucleus of the keratinocyte and shields the nuclear DNA from ultraviolet radiation. The darker tones of the skin result from melanin produced by melanocytes.
Tactile cells, also called Merkel cells,are few in number and found scattered among the cells within the stratum basale. Tactile cells are sensitive to touch and, when compressed, they release chemicals that stimulate sensory nerve endings,providing information about objects touching the skin.
cell division to produce new keratinocytes.
stratum germinativum undergo mitosis and reproduce themselves.
1st is epidermis, 2nd is subcutaneous and last, the dermis, which is the deepest layer
The Stratum Basale
In germinative layer: the stratum basale and stratum spinosum of the epidermis considered as a single layer; the term is sometimes used to denote only the stratum basale.
Cell division occurs in the stratum basale of the epidermis. The epidermis is made up of 5 layers. From outer to inner these layers are: stratum corneum, stratum licidum, stratum granulosum, stratum spinosum, and stratum basale. The basale is the innermost layer of the epidermis and is where cell division occurs.
The stratum basale and the stratum spinosum together are called the epidermis.
The stratum corneum is superficial to the stratum basale. The stratum basale is deep to the stratum corneum.
what occurs in the stratum basale
stratum germinativum is also know as stratum basale
1st is epidermis, 2nd is subcutaneous and last, the dermis, which is the deepest layer
The Stratum Basale
No. They are found in the lowest layer of the epidermis (stratum basale)No. They are found in the lowest layer of the epidermis (stratum basale).
In germinative layer: the stratum basale and stratum spinosum of the epidermis considered as a single layer; the term is sometimes used to denote only the stratum basale.
No. The Stratum Granulosum is deteriorating organelles. The Stratum Basale, or Stratum Germinativum, is the "Germinating layer". The most rapid cell division occurs here, of course, because it's closest to the vascular dermis.
The stratum basale is found in the skin. It is one of the layers of the epidermis.
Stratum basale, stratum spinosum, stratum granulosum,stratum lucidum & stratum corneum
Cell division occurs in the stratum basale of the epidermis. The epidermis is made up of 5 layers. From outer to inner these layers are: stratum corneum, stratum licidum, stratum granulosum, stratum spinosum, and stratum basale. The basale is the innermost layer of the epidermis and is where cell division occurs.
Nail matrixStratum Basale.