This all depends on the year of the car. A 2010 Acura MDX 4WD is 16 miles for the city and 21 for the highway. This can all vary depending on many different factors, that are up to you.
2007 MDX Sport 20 normal driving, 23 highway
The 2003 Acura MDX is a gas-powered vehicle.
The 2013 Acura MDX is a gas-powered vehicle.
The 2007 Acura MDX is a gas-powered vehicle.
The 2002 Acura MDX is a gas-powered vehicle.
The 2001 Acura MDX is a gas-powered vehicle.
The 2006 Acura MDX is a gas-powered vehicle.
The 2008 Acura MDX is a gas-powered vehicle.
The 2010 Acura MDX is a gas-powered vehicle.
The 2005 Acura MDX is a gas-powered vehicle.
The 2009 Acura MDX is a gas-powered vehicle.
The 2014 Acura MDX is a gas-powered vehicle.