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What is the general features of allosteric regulation using the feedback inhibition?
Wiki User
∙ 10y ago
enzymes situated at key steps in metabolic pathways are modulated by allosteric effectors
these effectors are usually produced elsewhere in the pathway
effectors may be feed-forward activators or feedback inhibitors
kinetics are sigmoid ("S-shaped")
Wiki User
∙ 10y ago
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What is found in allosteric enzymatic regulation?
An allosteric enzyme is one in which the activity of the enzyme can be controlled by the biniding of a molecule to the "allosteric site". This really just means somewhere other than the active site. Thus allosteric control of an enzyme can be classed in two ways. A positive allosteric modification is the binding of a molecule to the enzyme which increase the rate of reaction. Sort of like catalysing the catalysing effect of an enzyme. Obviously the opposite is true of negative allosteric modification. A good example for this is the activity of phosphofructokinase, which is promoted by a high AMP concentration, and inhibited by a high ATP concentration. This should make sense if you think about the action of a kinase etc.
End products of biosynthetic pathways often act to block the initial step in that pathway This phenomenon is called?
metabolic inhibition
Regulatory device in which the product of a pathway binds to an enzyme early in the pathway?
feedback inhibition
The body mechanism in which the product or result of a process stops or limits the process?
Feedback inhibition
How do target organs most often regulate the pituitary gland?
Negative feedback inhibition
When a pathway is subject to allosteric feedback inhibition ...?
an accumulation of effectors slows the pathway.
Some enzymatic regulation is allosteric In such cases which of the following would usually be found?
an enzyme with more than one subunit, not feedback inhibition.
Do you think that feeling of fullness and hunger are examples of feedback inhibition?
The feeling of fullness and hunger are examples of the negative feedback inhibition.
What is found in allosteric enzymatic regulation?
An allosteric enzyme is one in which the activity of the enzyme can be controlled by the biniding of a molecule to the "allosteric site". This really just means somewhere other than the active site. Thus allosteric control of an enzyme can be classed in two ways. A positive allosteric modification is the binding of a molecule to the enzyme which increase the rate of reaction. Sort of like catalysing the catalysing effect of an enzyme. Obviously the opposite is true of negative allosteric modification. A good example for this is the activity of phosphofructokinase, which is promoted by a high AMP concentration, and inhibited by a high ATP concentration. This should make sense if you think about the action of a kinase etc.
The process by which the product of a system shuts down the system or limits its operation is called the inhibition?
feedback inhibition
What describes a process the cell use to control metabolism?
feedback inhibition
What term a process the cell uses to control metabolism?
feedback inhibition
What term describes a process the cell to control metabolism?
feedback inhibition
Why is ACTH elevated in Addisons disease?
The steroid hormones produced by the adrenal cortex exhibit feedback inhibition on ACTH production, therefore a low concentration of corticosteroids (as seen in Addisons disease) will not exhibit this feedback inhibition. Without this inhibition, ACTH levels are not regulated and therefore rise.
Is an allosteric site of an enzyme often involved in feed back inhibitition?
yes it can be. as the enzyme produces more of a product if that product becomes too many then one will bind to the allosteric site of the enzyme haulting its own production. (negative feedback). and the same thing can happen for positive feedback
End products of biosynthetic pathways often act to block the initial step in that pathway This phenomenon is called?
metabolic inhibition
How do target organs most often regulate the pituitary gland?
Negative feedback inhibition
