Onarga (EXIT 280 off I-57)
Minturn, Colorado.
Bevis, Ohio
There aren't many towns on that whole stretch of I-5. Wasco is the closest to halfway.
The halfway point between Chicago Illinois and Winnsboro Texas is Portageville, Missouri.
Thornton, IN
It depends greatly on whether you take the fastest route or the shortest route. If you take the freeway to Greensboro and then north on US-29, your halfway point between Kernersville and Danville is on US-29 between Greensboro and Reidsville, near Browns Summit, NC. If you take US-158 across, then your halfway point is on US-158 on the southwest side of Reidsville
Van Buren Point, New York is halfway between Chicago & Montpelier
Atlantic IA, I-80 exit 60 is pretty close to the middle of the trip.
lisbon
Hubbard, OH
Cave, Missouri is halfway between Fayetteville & Chicago
Cheyenne, WY