There is no landing site halfway between the UK and Panama. That would be the Atlantic Ocean.
Gloucester, UK is halfway between Bath & Birmingham
The halfway point between London in England (United Kingdom) and Aylesbury in England (UK) is Watford. Watford is in England (UK).
Nottingham is the half-way point between Bath, UK and Durham, UK. Nottingham is famed for its links to the legend of Robin Hood.
The geographic halfway point between London in England (United Kingdom) and Nottingham in England, (United Kingdom) is Northampton, also in England (UK). The halfway point co-ordinates are 52° 12' 8" N and 0° 55' 20" W.
Huntingdon, in Cambridgeshire
If you swing south, your halfway point along the coast would be around Bournemouth. If you swing north, your halfway point along the coast would be Bristol, which is less scenic but it's a direct shot on the M4 and M5.
Arnold, UK
Cheltenham
A good halfway meeting point between Leeds and San Francisco would be an airport or airport hotel near the East Coast of the United States. So any airport or airport hotel around New York or Philadelphia would be convenient.
Refueling points are normally halfway and include Singapore, Hong Kong and Dubai
Birmingham UK or Birmingham Birmingham, Alabama
There is no ideal travel destination halfway between Detroit Michigan and England. You would be over the Atlantic Ocean.