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Crimean-Congo,SARS,Typhoid Fever,Yellow Fever,Cholera,malaria,Avian Influenza,Marburg Virus,Ebola Virus,HIV,anthrax. all top the charts worldwide and all caused global responce like th h1n1 virus also unsure about the bubonic plague

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Q: What is the most deadliest virus ever instea of the Influenza?
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What is the difference between H1N1 H1N2 H3N2 and H3N1 viruses?

Overview:H1N1, H1N2, and H3N2 are the only known Influenza A virus subtypes currently circulating among humans. All the subtypes listed in the question, i.e., H1N1, H1N2, H3N1 and H3N2 are the known subtypes of influenza A viruses that are endemic in pigs and create influenza in pigs, from which reassortants have formed new strains that can be infective to humans. H1N1 is the "swine flu" subtype of influenza, of which there are several different strains. This subtype is usually seen in humans and pigs. The better known reassortant H1N1 virus strain currently circulating is H1N1/09, the pandemic swine flu virus that caused the pandemic of 2009 and infected humans, pigs, birds, ferrets, dogs, and cats during the pandemic. There are several other less well known strains of the H1N1 subtype.H1N2 is a common flu in pigs in the Upper Midwest of the US. Until 2011, only one case had been known to occur in humans and that was in 2007 in Michigan. 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Referred to as the "H" in influenza viruses.Neuraminidase: An important surface structure protein of the influenza virus that is an essential enzyme for the spread of the virus throughout the respiratory tract. It enables the virus to escape the host cell and infect new cells. Referred to as the "N" in influenza viruses.See more about the lytic cycle and influenza virus nomenclature in the related questions below.Types of Influenza VirusesThere are three types of influenza viruses: Types A, B and C. Influenza A and B viruses cause seasonal outbreaks and epidemics of influenza virus infections each flu season. Type A causes all pandemics. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Influenza A viruses are divided into subtypes based on the configuration of the two proteins on the surface of the viruses: hemagglutinin (H) and neuraminidase (N). [Not all H1N1 viruses are the same; not all H5N1 viruses are the same.....etc] There are 16 different hemagglutinin subtypes and 9 different neuraminidase subtypes. Influenza A viruses can be further broken down into different strains.Influenza B viruses are not divided into subtypes. Influenza B viruses also can be further broken down into different strains.Influenza A (H1N1), A (H3N2), and influenza B strains are included in each year's influenza vaccine. Getting a flu vaccination can protect against influenza A and B viruses. The flu vaccine does not protect against influenza C viruses.More information including how influenza viruses change: Drift and ShiftInfluenza viruses are dynamic and are continuously mutating, reassorting, and evolving. Influenza viruses can change in two different ways: antigenic drift and antigenic shift. Influenza viruses are changing by antigenic drift all the time, but antigenic shift happens only occasionally. 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