8
The difference is that a patient with sickle cell disease has an increased level of one specific type of Hemoglobin, that is Fetal hemoglobin or HbF. However, the amount of total hemoglobin is the same.
Hemoglobin S. This the predominant hemoglobin in people with sickle cell disease. The alpha chain is normal. The disease-producing mutation exists in the beta chain, giving the molecule the structure, a2bS2. People who have one sickle mutant gene and one normal beta gene have sickle cell trait which is benign.
Hemoglobin levelscan rise above the normal range, and it can be indicative of a number of disorders, such as congenital heart disease, pulmonary fibrosis, or an increase level of erythopoietin.
The amino acid sequence of the sickle cell allele for hemoglobin varies from the normal allele for hemoglobin by one amino acid. The sickle cell allele for hemoglobin has valine instead of glutamic acid. When the oxygen level of the blood decreases, the hemoglobin molecules come out of solution, stick together, and form long chains that cause the red blood cells to become sickle shaped.
For an infant, normal hemoglobin is 14-22 g/dL
Neither. People with sickle cell anemia have the same number of chromosomes and even the same number of genes as those who don't have the disease. The difference is a *change* in one of the genes. Actually, it is (usually) caused by a one letter difference in the hemoglobin gene which makes the hemoglobin produced more 'sticky' on a molecular level.
The normal hemoglobin level ranges from 12-18 grams per deciliter. Above normal hemoglobin levels may result in dehydration, excess production of rbc in bone marrow and other conditions.
12-17
A hemoglobin level of 11.7 g/dL is considered low for adult males. Normal hemoglobin levels for adult men typically range between 13.8 to 17.2 g/dL. It is advisable to consult a healthcare provider for further evaluation and management if the hemoglobin level is low.
sickle cell trait is a gene inherited from one parent which gives partial immunity to malaria and but is unlikely to develop into sickle cell anemia.The same gene inherited from BOTH parents causes Sickle-cell anemia, a blood disorder in which the body produces abnormal type of hemoglobin in red blood cells and can be deadly.
people with sickle cell disease have no abnormal appearances. the abnormalities are found on the microscopic level when the blood cells are examined.
A hemoglobin level of 18.7 g/dL is higher than normal and is known as polycythemia. This could be caused by various conditions like dehydration, lung disease, or bone marrow disorders. It is important to consult a healthcare provider to determine the cause and decide on appropriate management.