Director is non-gender specific and applies to both male and female directors
If you mean opposite gender, then the answer is manager.The noun 'manageress' is an obsolete word for a manager who is female.The noun 'manager' is a common gender noun, a word for a male or a female in charge.
Doctor is a neuter gender
Opposite gender of Filipino: Filipina
Clot is not gender specific.
Opposite gender of a Filipino: FILIPINA
The opposite gender of farmer is farmeress or farmwife.
The opposite gender of fraternity is sorority.
An emperor is the opposite in gender to an empress.
The opposite gender of giantess is giant.
The opposite gender for Joseph is Josephine.
The opposite of dairymaid is dairyman.