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What is the order of drug addiction?

Updated: 8/21/2019
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Q: What is the order of drug addiction?
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Tolerance to a drug (so that higher and higher amounts are needed in order to obtain the same initial effect) and dependence - both are part of the physical addiction. Psychological addiction does not involve physical tolerance and dependence, but can be difficult to treat, unless there is motivation to kick the habit.


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Addiction is caused by changes brought about in the brain by drug use, which cause the individual to need the drug in order to function. "Allergy" was the explanation used in the mid-20th Century, when we knew much less about addiction than we know today. While there is some genetic predisposition to addiction -- especially to alcohol -- addiction does not qualify as an allergy, which is an abnormal response of the immune system with an entirely different mechanism.


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