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Use a method called titration, where a known concentration of either a strong acid (to measure a weak base) or a strong base (to measure a weak acid) is slowly added to a solution of the unknown compound. By measuring the pH of the solution as you do the titration, and by measuring the volume of the known solution that you added to the unknown, you can determine the pKa of the unknown compound.
For complete instructions on how a titration is performed, see the Web Links to the left of this answer.
how can i determine pka value if pH is given?
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∙ 12y ago
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How you can select buffer in hplc according to pka value?
By following + or - 2 pH to the pKa value
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100mjkg1
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4.0
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What is PKa value of benzyl alcohol?
pKa = 15
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It is around pKa=13
How you can select buffer in hplc according to pka value?
By following + or - 2 pH to the pKa value
What is the pka value of ether?
The pka of a protonated ether (the conjugate acid) is about -3.5
What is pka value for sodium hydride?
The conjugate acid is Hydrogen (H2), the pKa of which is 35.
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3.3
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7.6
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if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
What is the calorific value of naphthalene?
100mjkg1
What is calorific value of naphthalene?
100mjkg1
Is there a pKa value for CO2 plus H2O - H2CO3?
pKa = 6.36 of carbonic acid to HCO3-
