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4-Aminonicotinic acid is one of the key synthetic intermediates of therapeutic drugs for cardiovascular and cerebrovascular diseases. There is a novel four-step synthesizing route of 4-aminonicotinic acid starting from isoquinoline and 3,4-pyridine dicarboxylic acid,and its overall yield of 4-aminonicotinic acid can be up to 30%(based on isoquinoline).
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∙ 11y ago
4-Aminonicotinic acid can be prepared by the reduction of 4-nitronicotinic acid with a reducing agent, such as sodium borohydride or iron powder. The reaction typically takes place in an aqueous or alcoholic solution, and the product can be isolated through filtration or crystallization. Additionally, the 4-aminonicotinic acid can be further purified by recrystallization or column chromatography.
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What type of preparation is used in acetic acid dilution?
Simply mix water and acetic acid to the desired concentration.
Why you use concentrated nitric acid in preparation of ammonium ferric sulphate?
Nitric acid being an oxidizing reagent help the oxidation of Fe(II) to Fe(III).
Preparation of aldehydes from nitriles?
Nitrile can be reduced into aldehyde using Raney Ni and formic acid or You can use DIBAL.
What accompanies the conversion of pyruvate to acetyl CoA in preparation for the citric acid cycle?
synthesis of NADH and release of CO2
Industrial method of preparation of Fumaric Acid?
1. Maleic anhydride is hydrated. This produces maleic acid. 2. Maleic acid is isomerised in the presence of a catalyst. 3. Fumaric acid is produced. Easy as that! (Except the temperature and pressure have to be kept controlled throughout)
How do you make anthranilic acid?
preparation of anthranilic acid
How does sulfuric acid catalyze the preparation of esters Could some other acid be used?
The concentrated sulphuric acid solution is the preferred catalyst for the preparation of esters. Rarely used is the hydrochloric acid as a gas.
Why hydrogen of COOH group is removed in preparation of methy salicylate from salicylic acid in the presence of sulphuric acid?
why hydrogen of COOH group is removed in the preparation of methyl salicylate from salicylic acid in the presence of sulphuric acid
Why is sulphuric acid not used in preparation of carbondioxidei?
because sulphuric acid stops reaction
What element needed in preparation of sulfuric acid?
sulfur
Equation of laboratory preparation of acetic acid?
it was prepared by using salycyclic acid when reacts with acetic anhydride in presence of sulphuric acid
Which acids are useful?
hydrochloric acid-preparation of aqua regia sulphuric acid- in car batteries acetic acid - in food preservatives
Chemical reaction in the preparation of citric acid from calamansi?
prepare citric acid using reformatsky reaction
Preparation of pyruvic acid from tartaric acid?
on heating the tartaric acid, the tartaric acid forms a keto acid which is known as pyruvic acid C4H6O6 ------KHSO4/heating------> C3H4O3 (tartaric acid) (Pyruvic acid)
What is the function of sodium bicarbonate in the preparation of hippuric acid?
neutralizing agent
What type of preparation is used in acetic acid dilution?
Simply mix water and acetic acid to the desired concentration.
Why do you use sulfuric acid in the preparation of banana oil experiment?
Sulfuric acid functions as a catalyst in the synthesis of banana oil.
