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The Ames assay is a pre-clinical testing assay that uses bacteria to determine if a compound causes genetic damage. It is used by a variety of companies (pharmaceutical, cosmetic, petroleum) to assess whether or not new compounds cause DNA damage and thus, potentially, cancer.
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What is the purpose of the ames test?
The Ames test identifies chemical mutagens.
Describe the principle of the Ames test for identifying chemical carcinogens?
A test used to determine the mutagenic potential of a substance based on the mutation rate of bacteria that are exposed to the substance.
What is the principle behind alkaloidal test?
to find out if the substance is acid or akaline
Can you reduce animal killing using AMES test?
not with ames but with animes
Are substances that test positive with the Ames test necessarily carciongenic in humans?
The substances that are test positive with Ames test may or may not be carcinogenic for humans. Similarly, some substances that cause cancer in laboratory animals do not give a positive result Ames test. It is not possible to decide the carcinogenicity of any substances only depending on the Ames test.
What is the principle behind the kraut's test for lipids?
Kraut's test for lipids is a test for glycerol. One of the reagents used in Kraut's test for lipids is bismuth subnitrate
In what field of science would one carry out an Ames test?
Ames test would typically be carried out in the field of biology, more specifically toxicology. The Ames test involves testing genetics, which involves taking a sample and examining it closely in a laboratory.
What is the test used for detecting chemicals with carcinogenic potential?
The Ames Test
Describe the control component in an Ames Test?
The Ames test is a quick method that uses bacteria to assay for cancer causing chemicals. A false positive is possible when a nitrogen based material is used.
What is the principle behind the shinoda test for flavonoids?
In the Shinoda test for flavonoids, a sample is added to pieces of magnesium and then hydrochloric acid is dripped on the sample. The color the sample turns indicates if there are flavonoids present or not.
Purpose of liver extract in the Ames test?
Ames test is used to test whether a certain substance is mutagenic. Liver extract is optionally added to simulate the effect of metabolism, as some compounds, like benzo[a]pyrene, are not mutagenic themselves but their metabolic products are.
Principle of widal test?
same principle for latex methd
