Amputation.
Massive internal bleeding caused by high pressure in the portal vein occurs in about 40% of patients with cirrhosis. Patients who survive are likely to need a portal vein bypass to control bleeding.
mostly occurs in the legs, but is sometimes seen in the arms
PAD most often occurs as a result of atherosclerosis
One of the major causes of peripheral arterial disease in the developed world is diabetes mellitus. This condition, if blood glucose levels are not well controlled, is associated with peripheral arterial disease which characteristically effects the kidneys and the retina of the eye. Damage to the micro-circulation occurs as well as disease of the larger vessels. Such processes lead to damage of the peripheral nerves, leading to anaesthesia (total numbness).Elevated serum levels of LDL-Cholesterol are also associated with damage to the peripheral arteries. Other causes include tobacco smoking.One of the most important causes of Peripheral Artery Disease is said to be Atherosclerosis which mainly occurs when the fatty deposits build up in the walls of your artery and as a result could reduce the blood flow in the body. The least common cause of Peripheral Artery Disease is said to be blood clotting in the arteries, injury to the limbs.
Peripheral blood flow refers to the circulation of blood through the blood vessels outside of the heart and lungs, supplying oxygen and nutrients to the body's tissues and organs. It is regulated by mechanisms that control blood vessel diameter and blood pressure to ensure adequate oxygen delivery to all parts of the body. Disorders affecting peripheral blood flow can lead to conditions such as peripheral artery disease or Raynaud's disease.
Arterioles
Nerves
When atherosclerosis occurs in a limb, it is referred to as peripheral artery disease (PAD). This condition results from the narrowing of the peripheral arteries, often leading to reduced blood flow to the legs and feet. Symptoms may include leg pain, cramping, and, in severe cases, ulcers or gangrene. PAD is a significant risk factor for cardiovascular events and requires proper diagnosis and management.
Peripheral means somethig on the outskirts or borders. When referring to eyesight, it means vision that occurs outside the very centre of the eye
Chronic pulmonary disease and elevated pulmonary vascular resistance can lead to pulmonary hypertension. This condition occurs when there is increased pressure in the pulmonary arteries, which can strain the right side of the heart, potentially leading to right heart failure. Over time, the combination of chronic lung disease and elevated pressures can significantly impair respiratory function and overall cardiovascular health. Early diagnosis and management are crucial to mitigate these complications.
The vascular system, or respiratory system, deals with the exchange of oxygen to carbon dioxide. This exchange occurs in the alveoli sacs
DefinitionCollagen is a tough, glue-like protein that makes up 30% of body protein. It shapes the structure of tendons, bones, and connective tissues. Problems with the immune system can affect these structures. This is known as collagen vascular disease.Collagen vascular diseases include:DermatomyositisPolyarteritis nodosaRheumatoid arthritisSclerodermaSystemic lupus erythematosusSymptomsSymptoms of collagen vascular disease may include:AnemiaFeverJoint inflammationWeakness