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What are non-nucleoside reverse transcriptase inhibitors?
delavirdine (Rescriptor), loviride, and nevirapine (Viramune) act by binding directly to the reverse transcriptase molecule, inhibiting its activity.
What enzyme turns HIV rna into HIV DNA?
The enzyme is called reverse transcriptase. The class of HIV drugs that block this process are called reverse transcriptase inhibitors.
How many drugs have been approved for use against HIV?
There is no cure for HIV, however the drug classes that are used to treat HIV are Non-nucleoside reverse transcriptase inhibitors (NNRTIs), Nucleoside reverse transcriptase inhibitors (NRTIs), Protease inhibitors (PIs), Entry or fusion inhibitors, and Integrase inhibitors
What is a calanolide?
A calanolide is any of a family of reverse transcriptase inhibitors extracted from trees of the genus Calophyllum.
Which is the enzyme that HIV uses to synthesize DNA on an RNA template?
The enzyme that HIV uses to synthesize DNA on an RNA template is called reverse transcriptase. It catalyzes the conversion of viral RNA into DNA, which is an essential step in the HIV replication cycle.
Difference between nucleoside reverse trancriptase inhibitor and non nucleoside reverse transcriptase inhibitor?
They have a different mode of action in inhibiting the transcription of the viral DNA. The NRTI is actually a nucleoside that incorporates into the viral DNA but it does not have a 3-hydroxyl group so it inhibits and halts the continued growth of the viral DNA chain. The NNRTI's bind to the reverse transcriptase and inhibit its movement.
What services does ViiV Healthcare provide?
Viiv Healthcare provides several products and services for HIV treatment. They provide nucleoside reverse transcriptase inhibitors such as Combivir and Epivir and protease inhibitors such as Lexiva and Viracept.
What precautions should be taken when taking non-nucleoside reverse transcriptase inhibitors?
Patients should not discontinue this drug even if symptoms improve without consultation with a physician.
Can reverse transcriptase be denatured?
Yes, reverse transcriptase can be denatured under certain conditions. High temperature or extreme pH levels can disrupt the structure of reverse transcriptase, rendering it inactive. Denaturation of reverse transcriptase can prevent it from catalyzing the conversion of RNA into DNA during the process of reverse transcription.
Is AZT is a protease inhibitor?
No, AZT (zidovudine) is not a protease inhibitor; it is an antiretroviral medication classified as a nucleoside reverse transcriptase inhibitor (NRTI). AZT works by inhibiting the reverse transcriptase enzyme, which is crucial for the replication of HIV. Protease inhibitors, on the other hand, target the protease enzyme, preventing the maturation of viral particles.
What enzyme do viruses use to produce m-RNA?
reverse transcriptase
What enzyme is used in reverse transcription?
Reverse transcriptase is the enzyme used in reverse transcription to generate complementary DNA (cDNA) from an RNA template.
