5' cap helps protect mRNA from degradation by hydrolytic enzymes and after mRNA reaches the cytoplasm, the 5' cap functions as part of an "attach here" sign for ribosomes. The poly-A-tail inhibits degradation of RNA and helps ribosomes attach and facilitates export of mRNA from the nucleus.
it gives the tail a slight advantage over the others
5 cap protect rna from 5' exonuclease and 3' poly a tail protect mrna from 3' exonucleases
mRNA
a. transcription is initiated b. 5' cap is added c. introns are removed d. transcription is terminated e. 3' poly-A tail is added f. mRNA exists nucleus
Before leaving the nucleus, the mRNA is modified (post-transcriptional modification). It is protected from ribonucleases by adding a 5' cap and a (3') poly A tail. These modifications help to stabilise the mRNA by preventing degradation by nucleases.
An eukaryotic mRNA has 2 ends, a 3' (three prime) end and a 5' (five prime) end. They are both protected from degradation. The 3' end is protecting by a long tail of the Adenosine base, this tail is reffered to as the Poly-A tail and is established through the process of polyadenylation. The 5' end has a different method of protection from degradation, it undergoes "capping". Capping involves a Gaunine base paring in a 5' - 5' manner with the exposed 5' end of the mRNA. This basically leaves no exposed 5'. An eukaryotic mRNA has 2 ends, a 3' (three prime) end and a 5' (five prime) end. They are both protected from degradation. The 3' end is protecting by a long tail of the Adenine base, this tail is reffered to as the Poly-A tail and is established through the process of polyadenylation. The 5' end has a different method of protection from degradation, it undergoes "capping". Capping involves a Gaunine base paring in a 5' - 5' manner with the exposed 5' end of the mRNA. This basically leaves no exposed 5'.
in the transition from pre-mRNA to mRNA, there are two major events that transform the polynucleotide chain. The first, is a modification of the ends, on the 5' end, there is a G cap added ( a g cap is derived from gtp), this g cap both helps the binding to ribosomes and protects against the break down by ribonuclease, to the 3' end a modification is made where by the AAUAAA sequence(which signals the cleaving enzyme)is cleaved off and replaced by a poly A sequence (100-200 nucleotides long), which assists in the transport of the mRNA out of the nucleous, and is vital to the polynucleotide's stability. The second modification is when the introns are removed, leaving just the exons.Hope this was helpful, -Brother of Captain Yitz
5' cap and poly (A) tailPoly A tail at 3' end
mRNA
The 5' end receives a modified nucleotide 5' cap The 3' end gets a poly-A tail
Prokaryotic mRNA lacks a 5' cap and 3' poly(A) tail because it undergoes rapid degradation in the cell. Prokaryotes do not have the same mRNA processing machinery as eukaryotes, so they rely on different mechanisms for stability and translation initiation, such as internal ribosome binding sites (RBS) and RNA-binding proteins.
a. transcription is initiated b. 5' cap is added c. introns are removed d. transcription is terminated e. 3' poly-A tail is added f. mRNA exists nucleus
Before leaving the nucleus, the mRNA is modified (post-transcriptional modification). It is protected from ribonucleases by adding a 5' cap and a (3') poly A tail. These modifications help to stabilise the mRNA by preventing degradation by nucleases.
An eukaryotic mRNA has 2 ends, a 3' (three prime) end and a 5' (five prime) end. They are both protected from degradation. The 3' end is protecting by a long tail of the Adenosine base, this tail is reffered to as the Poly-A tail and is established through the process of polyadenylation. The 5' end has a different method of protection from degradation, it undergoes "capping". Capping involves a Gaunine base paring in a 5' - 5' manner with the exposed 5' end of the mRNA. This basically leaves no exposed 5'. An eukaryotic mRNA has 2 ends, a 3' (three prime) end and a 5' (five prime) end. They are both protected from degradation. The 3' end is protecting by a long tail of the Adenine base, this tail is reffered to as the Poly-A tail and is established through the process of polyadenylation. The 5' end has a different method of protection from degradation, it undergoes "capping". Capping involves a Gaunine base paring in a 5' - 5' manner with the exposed 5' end of the mRNA. This basically leaves no exposed 5'.
in the transition from pre-mRNA to mRNA, there are two major events that transform the polynucleotide chain. The first, is a modification of the ends, on the 5' end, there is a G cap added ( a g cap is derived from gtp), this g cap both helps the binding to ribosomes and protects against the break down by ribonuclease, to the 3' end a modification is made where by the AAUAAA sequence(which signals the cleaving enzyme)is cleaved off and replaced by a poly A sequence (100-200 nucleotides long), which assists in the transport of the mRNA out of the nucleous, and is vital to the polynucleotide's stability. The second modification is when the introns are removed, leaving just the exons.Hope this was helpful, -Brother of Captain Yitz
Not necessarily in this order: It gets a 5' modified guanine cap It gets a 3' poly-A tail It visits a spliceosome. The introns are removed. The exons may undergo "alternative splicing" in which some of them are removed too, and the rest are spliced together to make one mRNA.
Three problems caused by a peacock's large tail include slows down the male, serves no useful purpose and makes him conspicuous to predators.
Poly Styrene was born on July 3, 1957, in Bromley, Kent, England, UK.
The 5-prime end is immediately capped off with a modified form of a guanine (G) nucleotide. This 5-prime cap has at least two important functions: protect the mRNA from degradation by hydrolytic enzymes and act as an "attach here" sign for ribosomes. The 3-prime end gains a poly(A) tail consisting of 30 to 200 adenine nucleotides, which also inhibits degradation of the RNA and helps ribosomes attach to it. The poly(A) tail also seems to facilitate the export of mRNA from the nucleus.