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What is the purpose of the Tensilon test?

Updated: 8/19/2019
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By blocking the action of acetylcholinesterase, Tensilon prolongs the muscle stimulation, and temporarily improves strength. Increased strength following an injection of Tensilon strongly suggests a diagnosis of MG.

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Q: What is the purpose of the Tensilon test?
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What is a Tensilon test?

Tensilon is the trade name for edrophonium chloride. The Tensilon test is an injection of edrophonium chloride used to diagnosis myasthenia gravis (MG).


What precautions need to be taken when using the Tensilon test?

The Tensilon test may cause heart rhythm abnormalities, especially in those patients with preexisting conditions.


How is the Tensilon test done?

The Tensilon test involves the intravenous injection of a small amount of Tensilon. The needle is left in place. If no adverse reaction is observed within 30 seconds, an additional volume is injected. Results are apparent within one minute.


What characteristics does a normal Tensilon test have?

In a patient without MG, the Tensilon test will not produce an obvious increase in a previously weak muscle. Some subjective feelings of increased strength are possible but not significant.


What care should a patient receive after a Tensilon test?

The effects of Tensilon subside quickly, and are completely gone after 30-60 minutes. No aftercare is needed.


Cpt ocde for myasthenia gravis tensilon test?

I cannot answer question. But maybe typo correction will help. Good luck.


How should patients be prepared for a Tensilon test?

Before the test, the patient must stop taking all drugs that can inhibit acetylcholinesterase. The referring physician can advise on specific drugs the patient is taking.


What risks exist for the patient in undergoing a Tensilon test?

Atrial fibrillation and bradycardia are possible in sensitive individuals. The administering physician must have appropriate resuscitative equipment available.


What characteristics does an abnormal Tensilon test have?

An obvious increase in strength in weakened muscles strongly suggests the diagnosis of myasthenia gravis. The effect comes on very rapidly, and fades within minutes.


Tensilon test?

DefinitionThe Tensilon test is a method to help diagnose myasthenia gravis.How the test is performedA drug called Tensilon (also called edrophonium) or a dummy medicine (inactive placebo) is given during this test. The health care provider gives the appropriate one through one of your veins (intravenously, through an IV). You may also be given a medication called atropine before receiving Tensilon so that you do not know you are receiving the drug.You will be asked to perform some repetitive muscular movements such as crossing and uncrossing your legs or getting up from a sitting position in a chair. Particular attention will be paid to whether your muscle strength is improved by the Tensilon.The test may be repeated and additional Tensilon may be given to help tell the difference between myasthenia gravis and other conditions.How to prepare for the testNo special preparation is usually necessary. However, you should follow any dietary restrictions or other directions prescribed by your health care provider.How the test will feelYou will feel a sharp prick as the IV needle is inserted. The drug may cause a feeling of a churning of the stomach or a slight feeling of increased heart rate, especially if Atropine is not given first.Why the test is performedThe test helps diagnosis myasthenia gravis, may aid in telling the difference between myasthenic and other similar neurological conditions, and may be used to monitor oral anticholinesterase therapy.What abnormal results meanIn myasthenia gravis, the muscles will improve immediately following the Tensilon. The maximum benefit only lasts a few minutes.In myasthenic crisis (worsening of the disease that requires anticholinesterase therapy), there is a brief improvement in the muscle strength.In cholinergic crisis (overdose of anticholinesterase), Tensilon will make the person even weaker.Additional conditions under which the test may be performed include Lambert-Eaton syndrome.What the risks areThe drug used during the test may cause side effects, including fainting or respiratory failure. Therefore the test must be done in a medically supervised setting.ReferencesVincent A, Newsom-Davis J. Disorders of neuromuscular transmission. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 448.


Purpose of the test in education?

The purpose of the test in education serves a double purpose. The test is an assessment of what the student has learned. It is also a measure of the quality of the teaching.


Atropine sulfate preoperatively?

atropine sulfate is used as an antidote of anticholinesterase meds administered on patients with myasthenia gravis. Atropine sulfate should be also made available when performing the Tensilon Test to reverse the effect of Edrophonium injection.