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What is the role of motif in signal transduction?
the role of Motif in signal transduction
What is the role of a G-protein?
They initiate signal transduction which consists of converting extracellular hormone signal to intracellular signal that creates an action.
What is serpentine receptor?
A serpentine receptor is a receptor in the cell membrane that plays a role in signal transduction.
What is the role of cAMP in the signal transduction pathway activated by epinephrine?
It binds to and activates protein kinase A, which then phosphorylates other enzymes.
What are CDKs?
Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating thecell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.[1] They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. In fact, yeast cells can proliferate normally when their CDK gene has been replaced with the homologous human gene.[1][2] CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain.[1] By definition, a CDK binds a regulatory protein called acyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.[1] The consensus sequence for the phosphorylation site in the amino acid sequence of a CDK substrate is [S/T*]PX[K/R], where S/T* is the phosphorylated serine or threonine, P is proline, X is any amino acid, K is lysine, and R is arginine [1]
Cyclins are a family of closely related proteins that do what?
Cyclins are regulatory proteins that play a crucial role in controlling the progression of the cell cycle by binding to cyclin-dependent kinases (CDKs) and activating them. They help regulate the timing and coordination of key events in the cell cycle, such as DNA replication and mitosis.
What role do transcription factors play in cell?
By binding to a plasma membrane receptor it initiates a cascade in a signal transduction pathway. They can activate yet more genes.
What are similarities of plant and animal hormones?
Animal and plant hormones play an important role in the growth and development of the species. They work by the existence of specific pathways, and complex signal transduction.
What is the role of G protein-coupled receptor?
To accept the ligand that properly fits the receptor sit. Then the G protein is activated and GDP is phosphorylated to GTP and the protein goes on to begin signal transduction in one of several ways open to G proteins.
Why did Martin Rodbell win The Nobel Prize in Physiology or Medicine in 1994?
The Nobel Prize in Physiology or Medicine 1994 was awarded jointly to Alfred G. Gilman and Martin Rodbell for their discovery of G-proteins and the role of these proteins in signal transduction in cells
Why is phosphorescence important?
Phosphorylation plays a critical role in the regulation of many cellular processes including: cell cycle, growth, apoptosis and signal transduction pathways. It is the most common mechanism of regulating protein function and transmitting signals throughout the cell.
Why did Alfred G. Gilman win The Nobel Prize in Physiology or Medicine in 1994?
The Nobel Prize in Physiology or Medicine 1994 was awarded jointly to Alfred G. Gilman and Martin Rodbell for their discovery of G-proteins and the role of these proteins in signal transduction in cells
