The first and second lines of defense are both components of innate immunity, that is defenses that are present at birth. The job of the first line of defense is to keep microbes out of the body. They include the skin, mucous membranes and their secretions and the normal flora. The second line of defense is activated once the microbe gets into the body. The second line of defense includes white blood cells (which "eat" invading microbes), inflammation (which is used to isolate the microbes and facilitate tissue repair), fever (which inhibits replication of microbes and enhances WBC performance), and antimicrobial substances.
the body's second line of defense against pathogens is the B cells.
The third line of defence against pathogens is called the Specific Immune Responce
Prevents the invasion of of pathogen into the body and acts as the first and second line of defence Agianst pathogens
The difference between the first and second line of defence is that the first line of defence is your physical barrier like your skin and it protects you from most pathogens entering your body and the sweat and oil on your skin prevent some pathogens from growing on your body. the second line of defence is when a pathogen makes it past the first line of defence your body can mount an immune response to the attack and destroy the invader. Whether or not the response succeeds depends very much on your body's ability to distinguish between cells that belong to it and cells that do not.
the body's second line of defense against pathogens is the B cells.
The second line of defence is the non specific, it includes antimicrobial proteins, phagocytes and other cells. - In this state to inhibit spread of invader through out the body. -Inflamation, is its hallmark and most important mechanism.
when it gets past the first line (the skin)
cellular defence
The body has three main lines of defense against pathogens. They are as follows:First line of defense: Skin, Mucous membranes, and Secretions of skin and mucous membranesSecond line of defense: Phagocytic white blood cells, Antimicrobial proteins, and the Inflammatory responseThird line of defense: Lymphocytes, and Antibodies
1) surface barriers include the skin and mucous membranes. Gastric Juice,: Concentrated hydrochloric acid (HCl) and proteases that destroy pathogens in the stomach 2) second line of defence: the non-specific defence mechanisms such as inflammation, fever, phagocytic leucocytes, anti-microbial proteins 3) third line of defence: specific defence: Antigen (Macrophages encounter a pathogen, they digest it and present the antigenic fragments on their surface to helper T lymphocytes) and Antibody (B lymphocytes )
Immunoglobulin A (IgA) is the main effector of the mucosal surface and is an important first line of defense against most pathogens. It is also found in saliva, tears, and colostrum. IgA is produced by plasma cells as polymeric IgA consisting of two or more monomers linked by the J (joining) chain. It is then transfered to the epithelium and secreted. It is believed to interfere with pathogen adherence. IgA is also found as a monomer in the serum where it is a second line of defence against pathogens.
The integumentary system (skin) and mucous membranes are the first line of defense. They provide a physical barrier against invasion of pathogens. Any break in this physical barrier, such as a cut, makes it easier for pathogens to enter your body.