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both are plasma membrane receptors located at the cell surface's membrane. both are proteins that are hydrophilic and therefore cannot cross the lipid bilayer and requires second messengers to communicate with the nucleus of cells. activation of the receptors will activate other molecules in the activating cascades and the numbers of affected molecules will increase geometrically. however, activation of such receptors will cause desensitization/adaptation of the receptors themselves. the disability to desensitize can result to serious diseases such as cancer.

Khairul Abu Bakar 2nd Year Medical Student National Univ.of Ireland, Galway

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Q: What is the similarity of G-protein receptor system and Tyrosine-kinase receptor system?
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