Thrombin
Thrombin
In the final step of blood clotting cascade, Thromboplastin activates the prothrombin to Thrombin. Then the activated thrombin helps in the conversion of Fibrionogen into Fibrin (Mesh like fibrils which forms the clot).
Conversion of fibrinogen into fibrin is important in blood clotting and preventing further blood loss. The enzyme responsible for the conversion process is thrombin.
The plasma protein that is converted to fibrin is fibrinogen.
Prothrombinase converts prothrombin into enzyme thrombin.
coagulation
Prothrombin-->Thrombin; Fibrinogen--> Fibrin (activated by thrombin)The sequence of blood clotting is called Coagulation.
Thrombin
Thrombin
Thromboplastin -> Prothrombin -> Thrombin -> Fibrinogen -> Fibrin
Coagulation studies-Prothrombin Time (PT), Coumadin therapy, Partial Thromboplastin Time (APTT, PTT), Thrombin Time (TT) Vleeding time (BT)
Thrombin
inhibiting the formation of prothrombin activator and the action of thrombin on fibrinogen
Thrombin
THROMBIN
Thrombin is prescribed when you have minor bleeding (it controls the bleeding), and if you bleed during surgery. This medicine is applied only to your skin or incision during surgery.