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Disappearing ink is a water-based acid-base indicator (pH indicator) that changes from a colored to a colorless solution upon exposure to air. The most common pH indicators for the ink are thymolphthalein (blue) or phenolphthalein (red or pink). The indicators are mixed into a basic solution that becomes more acidic upon exposure to air, causing the color change. Note that in addition to disappearing ink, you could use different indicators to make color-change inks, too.
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