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What kind of mutations results in a nonfunctional protein?

Updated: 9/17/2019
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Q: What kind of mutations results in a nonfunctional protein?
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When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?

The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.


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