XXY, Klinefilter's syndrome
Actually, they're not. Male Calicos are very rare - only about 1 in 300 Calico kittens are male - but they do exist. Unfortunately, a sex-linked genetic disorder kills most male Calicos when they're just kittens, so adult male Calicos are extremely rare and are considered valuable.
Calico cats are almost always female. This occurs because the gene that determines color is located in the X chromosome and two X chromosome produce females.
Males and females have different chromosomes, and the calico pattern is pretty much locked to the female chromosomes. Coat color in cats is a sex-linked trait. The genetic coding for displaying black or orange color is found on the X chromosome. The coding for white is a completely separate gene. Since males have only one X chromosome, they can only be orange OR black. Males cats with two X chromosomes and one Y chromosome can turn out to be calico, but they are usually sterile.
X chromosome inactivation
Males are rare, if they exist at all. The gene for the calico fur is carried by the female chromosome.
The Calico cat is very likely to be female. It is a genetic trait that seems to be tied into the same genetics that govern their coat color.
Yes they are. Males only need one x chromosome to express yellow color. Females need two x chromosomes with yellow coloring. An orange x chromosome coupled with any other color x chromosome usually creates a calico; which is why calico's are all female (2 x chromosomes). I have one and she's the sweetest cat ever :) hope that helped :)
Calico cats can be many different breeds, specifically the ones that come in a variety of colors, such as Manx, American Shorthair, British Shorthair, Persian, Japanese Bobtail, Exotic Shorthair and Turkish Van, etc. Only females can be calico because their sex chromosome is XX, allowing three colors, whereas male chromosome is XY, only allowing two or less. It is hard to explain but that is the reasoning behind the lack of male calico cats.
No, calico cats are pretty common. It is very rare to see a male calico cat, especially one that is full-grown, because almost all male calicos have genetic defects that kill them as kittens. Because of this, adult male calicos are incredibly valuable and have sold for thousands of dollars or more.
Most calico or tortoiseshell cats are female, and the males are sterile, since they only have one X chromosome.
Cats with splotches of different colors, such as calicos are almost exclusively female. The coloring is caused because the gene for each color is on the X chromosome. In females, there are two X chromosomes and each may have an allele for a different color, for instance orange or black. In each cell, one X chromosome "shuts down", creating patches of different colors where different chromosome have been "shut off". The only way to have a male calico is if the animal has Kleinfelter's Syndrome - meaning it has one Y chromosome and two or more X's.
sex-linked inheritance