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What must happen inside the cell for gene therapy treatment to be successful?
Wiki User
∙ 10y ago
n the simplest forms of gene therapy, the DNA must be integrated into the genome of the cell (it must become part of the regular DNA that is in the cell) so that it is replicated when the cell divides and passed on to all the daughter cells. In addition, it has to integrate into a part of the DNA so that it can be expressed so that it can make the missing protein.
There are other forms of gene therapy for particular diseases where temporary expression therapeutic gene is all that is needed. For example, to make a tumor susceptible to certain drugs to cure the patient. In this case, integration is not needed and the DNA needs only to get into the nucleus so the gene can be expressed.
Wiki User
∙ 10y ago
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