The liver.
This is why liver failure simultaneously leads to bleeding and clotting disorders.
liver
Liver is responsible for the production of the clotting factors. Liver is the main organ of metabolism.
The liver
Liver primarily, and the kidneys as well
The liver. It produces many of the major clotting factors that are circulated in your blood. Student Doctor.
the heart
The liver
clotting factors
the liver synthesizes all the clotting factors, and requires vitamin K to activate factors II, VII, IX and X. Reduced plasma concentration of coagulation factors occurs in liver damage, which is easily recognized by prolongation of prothrombin time, which depends on factors I, II, V, VII and X.
Vitamins are substances which are not produced by the body, and therefore are necessarily obtained from the diet.
An enlarged spleen can interfere with blood clotting. The spleen is a multifunctional organ that helps produce platelets, which serve to clot the blood.
platelets or thrombocytes