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The application of dichlorodiphenyltrichloroethane (DDT) is considered the original event that resulted in the evolution of pesticide resistance in some insects. The incident numbers among the pivotal events in the twentieth century since its first applications date to the 1940s. Immunity to the pesticide's toxic effects may be traced back to as early as 1947.

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Q: What original event resulted in evolution of insecticide resistance in some insects?
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