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What percentage of Caucasian Americans are carriers of the Cystic Fibrosis?
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Why do inherited diseases like hemophilia and cystic fibrosis occur?
They are caused by the genes that we inherit from our parents. Genes govern how our body is run. Cystic fibrosis is caused by a recessive alle. This means that both parents must be carriers of the alle responsible for cystic fibrosis. The parents don't have to have the condition themselves; they can be just carriers of the one alle that makes up the condition.
What does heterozygous have to do with cystic fibrosis?
people who are heterozygous for cystic fibrosis are not directly affected by the disease (although there is some evidence they have more chance of getting Asama) however they do still carry the gene for CF (they are carriers) this means if they have kids with another carrier they have a 25% chance of having a CF positive child (out of four one non effected, two carriers, and one diseased)
Why does a person with Cystic Fibrosis have the genotype cc?
Cystic Fibrosis is inherited as a recessive trait. This means that both parents have to carry the allele for the defect. Both parents are Cc which means that 25% of their children will be CC (homozyous dominant and will not be able to pass the recessive allele in subsequent generations, 50% will be Cc(carriers) and 25% will be cc (homozygous reccessive and have Cystic Fibrosis).
What is cystic fibrosis gene disorder?
The genes on each chromosome control specific functions of the human body. The gene on chromosome 7 produces a protein called cystic fibrosis transmembrane regulator. Mutation in the DNA level of chromosome 7 leads to the absence of this protein which leads to cystic fibrosis. Cystic fibrosis is a recessive disease. It means that both copies of the gene must be defective. An affected person will have abnormal cystic fibrosis transmembrane regulator gene on each chromosome 7. Therefore both biological parents must have an abnormal gene. One abnormal copy is inherited from each parent. A person with one normal gene and one abnormal gene is called a cystic fibrosis carrier. Cystic fibrosis carriers do not show any symptoms but they may pass the abnormal gene to their children. Therefore the parents can be either cystic fibrosis carriers or affected themselves.
What are is the percentages of a child not having cystic fibrosis with parents who both have the trait?
If both parents are just carriers of the gene that causes CF then there is a 75% chance that the child will not have CF. To break it down farther... 25% chance that they will have CF. 50% that they will be a carrier. 25% that they will have two normal genes.
Why can't natural selection eliminate cystic fibrosis allele?
The prevalence of CF carriers (meaning they carry one mutation) is 1 in 25 in the Caucasian population. Most people don't even know that they are carriers until they have a child with CF. That means that the CF allele can unknowingly be passed down through generations. Carriers are typically asymptomatic and there is evidence to support that the CF mutation protected our ancestors from fatal diseases. So natural selection actually played a role in the proliferation of CF carriers.
A couple who are both carriers of the gene for cystic fibrosis have two children who have cystic fibrosis What is the probability that their next child will be phenotypically normal?
If both parents are carriers on cystic fibrosis, just because two children may have the disease it doesn't mean that say,a further 3 children in future will be "normal". Inheriting genes is like a lottery. I can say though that because cystic fibrosis is recessive, every offspring born under carriers will always have a 75% chance of being phenotypically normal.
To be a cystic fibrosis carrier do your parents have to have a cystics fibrosis gene?
Yes, since the disease is a recessive inherted trait BOTH parents must carry the gene but will not have the disease itself. Approximately 30,000 people in the United States have cystic fibrosis. An additional ten million more-or about one in every 31 Americans-are carriers of the defective CF gene, but do not have the disease. The disease is most common in Caucasians, but it can affect all races.
Is it possible for a mother to have two kids with different father be born with cystic fibrosis?
Depends. If your mother has cystic fibrosis and your father is a carrier, there is a 50% chance that any of their children will have cystic fibrosis. If the father is not a carrier, no children will have cystic fibrosis, but they will all be carriers.
How disorder is inherited cystic fibrosis?
Cystic Fibrosis, is a recessive disease (meaning that both parents must be carriers of the cystic fibrosis gene, for the offspring to have a chance of being born with it). A child has a 25% chance (1/4) of being born with Cystic Fibrosis.
Why do inherited diseases like hemophilia and cystic fibrosis occur?
They are caused by the genes that we inherit from our parents. Genes govern how our body is run. Cystic fibrosis is caused by a recessive alle. This means that both parents must be carriers of the alle responsible for cystic fibrosis. The parents don't have to have the condition themselves; they can be just carriers of the one alle that makes up the condition.
What is the population in the world with cystic fibrosis?
they haven't been able to pinpoint an exact percentage, but it is a known fact that about 1 out of every 3,000 people will have cystic fibrosis and that over 10 million people are carriers of the cystic fribrosis mutation.
Why can Cystic fibrosis be inherited even if neither parent has the disease?
Cystic Fibrosis is an example of a disease inherited as an autosomal recessive genetic disorder. Both parents of a baby who has Cystic Fibrosis have one abnormal recessive gene and one normal dominant gene and are therefore, Cystic Fibrosis carriers. Carriers are said to be heterozygous because they contain one normal copy of the gene and one abnormal copy. A baby who inherits cystic fibrosis has inherited the abnormal gene from both parents and is therefore said to be homozygous recessive.
Who defeated the Japanese fleet with aircraft carriers?
Americans.
Can people be carriers of cystic fibrosis and not know?
There are no symptoms or anything in a carrier of cystic fibrosis. The only way to find out is to get tested, or if you have a child with cystic fibrosis, you must be a carrier, as well as your partner.
What does heterozygous have to do with cystic fibrosis?
people who are heterozygous for cystic fibrosis are not directly affected by the disease (although there is some evidence they have more chance of getting Asama) however they do still carry the gene for CF (they are carriers) this means if they have kids with another carrier they have a 25% chance of having a CF positive child (out of four one non effected, two carriers, and one diseased)
What is the genotype of an individual that is not affected with cystic fibrosis?
Let's call the gene "C." Capital C means no cystic fibrosis; lower c means cystic fibrosis, since it is a recessive gene. CC is a person who does not have cystic fibrosis and also is not a carrier. Cc indicated a carrier. cc shows a person with cystic fibrosis. In order for a child to have cystic fibrosis, its parents must be: 1. cc and cc (both have cystic fibrosis, so every child will as well.) 2. Cc and Cc (both carriers; 25% chance of having a child with cystic fibrosis) 3. Cc and cc (one parent is a carrier and one has cystic fibrosis; there is a 50% chance that the children will have cystic fibrosis.)
